Cover photo for Dominic J. Nompleggi's Obituary
Dominic J. Nompleggi Profile Photo
1950 Dominic 2021

Dominic J. Nompleggi

May 1, 1950 — August 27, 2021

Dominic J. Nompleggi, MD, PhD


Dominic, "Dom," always quiet and deliberate in action, left this earth in the same manner. He fought the good fight for nearly five years and he died peacefully at Brigham and Women's Hospital, Boston, on August 27, 2021 surrounded by his loving wife and children.

Dominic J. Nompleggi was born in Boston on May 1, 1950 to Dominic and Concetta "Tina" (Annessi) Nompleggi. He is survived by his wife Ann E. Brown and two daughters, Victoria "Tori" and Elizabeth "Libby". Dominic, an only child, leaves 4 nieces and 3 nephews as well as other extended family members.

Dr. Nompleggi lived in the Boston area. He graduated from BC High and then moved to Washington DC to attend Georgetown University. He spent nearly 14 years at Georgetown earning a BA in 1972, a MS in 1974, a PhD in 1977, and a MD in 1982. After completing his medical education, he returned to Boston to complete postdoctoral training; Dr. Nompleggi completed his internship and residency at New England Deaconess Hospital. He served as Chief Resident at the hospital prior to completing clinical and research fellowship in Nutrition and Gastroenterology at the Brigham and Women's Hospital/Harvard Medical School in Boston. His advanced training was completed in 1991.

Shortly after completing his training, he joined the UMass Memorial Medical School and Hospital in 1991. Dr. Nompleggi served on the staff for 30 years. He served as the Clinical Chief of Gastroenterology until 2004 and then the Chief of the Division of Gastroenterology for the remainder of his tenure. Professionally, he served on multiple system leadership committees including the UMass Memorial Medical Group Board of Trustees and the Compliance Committee. Dr. Nompleggi was a beloved member of the staff; he served as a mentor, educator, clinician, and friend to all. He will be remembered for his calm and inclusive demeanor, his thoughtful leadership, and his ability to make everyone feel special. He loved being a physician and cherished all the moments of his tenure.

Dr. Nompleggi moved to Worcester in 1994 with his wife Ann. Together they raised two daughters who were his pride and joy. He loved being a father and cherished each milestone his daughters achieved. As a family they loved to travel, seek out wonderful places to dine, and entertain family and friends. He was an active member of the community serving on boards including the Worcester Club and the Worcester Art Museum. Dr. Nompleggi was a member of Tatnuck Country Club, The Worcester Club, The Argonauts and AOA.

The family would like to thank all of the special people who helped him during this time, especially his friends Charlie, Fran, Jim, and John, in addition to his work family, including Chris, KB, and Maria who provided support and camaraderie. Finally, we must not forget his medical team including the many nurses, physical therapists, speech therapists, and physicians who provided such excellent care. We especially want to recognize two physicians: Robert Mayer, MD, who was Dom's oncologist at the DFCI, and Scott Swanson MD, who was his surgeon at the Brigham and Women's Hospital. Collectivity, their treatment plan allowed Dom to continue to remain a productive and valuable asset to his community and family.

Yes, Dom, Dad, you are loved and will be missed by many but especially by your girls!

Visiting Hours are Tuesday, September 7th from 4:00-7:00 pm at Callahan, Fay & Caswell Life Celebration Home, 61 Myrtle Street. The Funeral will be held Wednesday, September 8th with a Mass of Christian Burial at 11:00 am at Our Lady of the Angels Church, 1222 Main Street, Worcester. Interment will be private and held at a later date.

In lieu of flowers, gifts in memory of Dominic J. Nompleggi, MD, may be made in support of the Dominic J. Nompleggi, MD, Fund. Gifts can be made online at or mailed to:
Office of Advancement
UMass Medical School
333 South Street
Shrewsbury, MA 01545
Checks should be made out to "UMass Medical School Foundation – Dominic J. Nompleggi, MD, Fund" and should note that the gift is in memory of Dominic J. Nompleggi, MD.
Or to,
Dana-Farber Cancer Institute in memory of
Dominic Nompleggi to support cancer research and patient care at:
Dana-Farber Cancer Institute
P.O. Box 849168
Boston, MA 02284
or via
To order memorial trees or send flowers to the family in memory of Dominic J. Nompleggi, please visit our flower store.

Service Schedule

Past Services

Visiting Hours

Tuesday, September 7, 2021

4:00 - 7:00 pm (Eastern time)

Callahan, Fay & Caswell Life Celebration Home

61 Myrtle St, Worcester, MA 01608

Enter your phone number above to have directions sent via text. Standard text messaging rates apply.

Funeral Mass

Wednesday, September 8, 2021

Starts at 11:00 am (Eastern time)

Our Lady of Angels Church

1222 Main St, Worcester, MA 01603

Enter your phone number above to have directions sent via text. Standard text messaging rates apply.


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